Fumed Silica, well known by its trade names Aerosil® and Cab-o-sil®, is very difficult to disperse for a number of reasons. The powder is extremely low density so tends to float on the surface of the liquid base.
Conventional mixers and stirrers aren’t capable of rapidly incorporating the powder and activating its thickening effect so formulations often contain excessive amounts of Fumed Silica to compensate for this.
Due to the fineness of the powder, dusting can also cause problems. The high shear action of a Silverson Machines, Inc. mixer can solve these problems while also improving your product quality, stability and mixing times.
Integrated Process Engineers & Constructions, Inc., also known as IPEC, has been providing a wide range of custom modular process systems and components for the pharmaceutical, biotech, food, dairy, chemical, and biofuel industries since 1996. IPEC designs and fabricates complex systems from start to finish.
CESCO was involved in a Media & Buffer Prep System project with IPEC for a large pharmaceutical company. Above are pictures of the final system during the Factory Acceptance Test.
From left to right: Yogurt Blending Skid, Yogurt Blending Skid, Sour Cream Blending Skid
By utilizing flow meters, positive displacement pumps, control values, static mixers and other process sensors, IPEC is able to design and construct blending systems to incorporate ingredients into a continuous product stream. Ingredients can be supplied from totes or skid-mounted vessels while instrumentation and mechanical components work together to blend ingredients dynamically and accurately to user-defined ratios and production rates. Integrated CIP capabilities, product recovery (pigging) systems, and alternating ingredient vessels (for continuous production) are available.
IPEC recently delivered Ultrafiltration/Diafiltration (UF/DF) and Virus Filtration systems to a pharmaceutical client. The customer came to IPEC with desired production rates and preferred 3rd party filtration technologies, and asked that IPEC assist with process development.
Alfa Laval’s service network is comprised of skilled and knowledgeable workers to assist in minimizing cost and maximizing return on your company’s equipment investment. With the use of Alfa Laval’s service network, companies are able to utilize their equipment for as long as they desire. The Alfa Laval Service Network prevents unplanned interruptions, promotes operation efficiency, and adapts to unique challenges.
360° Service Portfolio
Alfa Laval’s 360° Service Portfolio offers support for all stages of the equipment’s lifecycle;– from planning, installation and commissioning to advice on the best replacement if the time comes. The company provides a variety of services that match your company’s needs. Alfa Laval’s global service network follows guidelines that ensure quality, safety and minimized environmental impact.
Benefits of Reconditioning your Gasketed Plate Heat Exchanger include:
An extension in life time
Minimize operational costs
Ensures safety, quality, and productivity
Satisfy new environmental legislation by improving energy efficiency.
Alfa Laval Parts
By utilizing genuine Alfa Laval parts, you can maximize the uptime of your equipment. Alfa Laval spare parts are designed for durability, reliability, and productivity. Using non-Alfa Laval parts could put your property, equipment, workers, and the environmental at risk.
Silverson has specialized in the manufacturing of quality high shear mixers for processing and manufacturing industries world wide for more than 70 years. Silverson has become the leader in the field of high shear mixers while serving food, pharmaceuticals, cosmetics, luboils and petrochemical industries.
The company supplies a wide range of standard mixers as well as custom designed equipment to meet an individual customer’s requirements. Developing and applying new high shear mixing techniques to meet these needs, Silverson has the experience, knowledge and commitment to both quality and service to solve today’s mixing needs and those of the future.
Silverson’s batch mixers emulsifies, homogenizes, solubilizes, suspends, disperses and disintegrates solids in addition to mixing. Silverson mixers outperform conventional mixers due to their precision-engineered Silverson rotor/stator workhead. As a result, it is able to cut process times by up to 90%. These mixers improve quality, product consistency and process efficiency.
The action of any Silverson In-Line mixer can be modified with the use of rapidly interchangeable workheads. This enables any machine to mix, emulsify, homogenize, solubilize, suspend, disperse and disintegrate solids.
Silverson’s line of high shear In-Line mixers offers a great many advantages to the processor:
The Silverson Flashmix takes a revolutionary approach to powder/liquid mixing by using a vacuum to pull in powders and forces powder into the liquid stream. This allows liquid to disperse and hydrate large volumes of powders and can be used at higher temperatures and with higher viscosity mixes. The Flashmix offers the advantages of high shear mixing to a wide range of applications that were previously not possible.
Gasketed Plate-And-Frame Heat Exchangers provide efficient heat transfer in compact equipment with a small footprint. The units have a flexible design and are easy to service and maintain. The product range is extremely wide and is used in duties for heating, cooling, heat recovery, evaporation and condensation in industries ranging from HVAC, refrigeration, engine cooling, dairy and food to heavier processes like chemical processing, oil production and power generation.
For more information regarding Alfa Laval’s Gasketed Plate-And-Frame Heat Exchanger line, click here.
Alfa Laval Services
Reconditioning your Gasketed Plate-And-Frame Heat Exchanger can:
Extend The Heat Exchangers’ Life
Minimize Operational Costs
Ensure Safety, Quality And Productivity
Satisfy New Environmental Legislation By Improving Energy Efficiency
Alfa Laval offers a number of pre-defined reconditioning packages, or customize a package of reconditioning services, to match your requirements for turnaround time, budget, brand and/or application.
Equipping your Heat Exchanger with the correct quality material can make a huge difference to your process. Alfa Laval genuine plates are made using a single-step pressing method ensuring uniform plate strength and thickness over the entire plate – dramatically reducing the risk of fatigue cracking. Alfa Laval genuine rubber gaskets ensure tighter seals and a longer life.
Steridose was founded in the late 1970’s in Sweden with the purpose of developing innovative process components for aseptic manufacturing. Steridose introduced technologies such as magnetically driven mixers and radial type diaphragm valves to the pharmaceutical industry in the 1980’s. In the early 2000’s, the company became part of the Roplan Group, consolidating development and manufacturing. Through the years, Steridose has developed an extensive distribution network with representation in over 30 countries and has a vast equipment installed base. Steridose continues innovating based on the feedback and needs of customers. In 2015, Roplan and Steridose formed Velcora Group.
The most common purpose of agitation in bio-pharmaceutical processing is liquid/liquid and solid/liquid blending (solutions and suspensions). Agitators are performing their duty while submerged in a ﬂuid phase, and consequently designed for this intended use, considering that running in air would not ﬁt any purpose. This article discusses different bearing designs and materials of construction typically available. Click here to read White Paper.
The Sterimixer may be the most widely used magnetically coupled mixer for bio-pharmaceutical applications world-wide. It consists of the following major components: impeller, bearing, weld-plate, drive unit and control box. All wetted parts of the impeller and the weld-plate are made of AISI 316 L (EN 1.4404). Interchangeable impeller designs are available.
CESCO was involved in the successful sale and installation of a LAKOS filtration skid at an inorganic chemical plant in North Carolina. The equipment was installed in between their cooling tower system and important process heat transfer equipment being fed by the tower water.